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  • 執筆者の写真hkytara

TARA Seminar on Nov. 27

A TARA seminar will be held as follows.

Date: Tuesday, November 27th, 2018 Time: 13:00-14:00 Venue: Seminar room, 2F, Bldg. A, TARA Center [Map

Speaker: Tudorita Tumbar, Ph.D. (Professor, Department of Molecular Biology and Genetics, Cornell University, USA)

Subject: “Molecular mechanisms of hair follicle stem cells function in normal homeostasis of adult skin”

Summary: Hair follicle stem cell function is governed by transcription factors, epigenetic mechanisms, and molecular cross-talking with the microenvironment. We found that the transcription factor Runx1 controls hair follicle stem cell activation and epithelial skin tumorigenesis. Recently, we found that Runx1 remodels the vasculature arrangements around the hair follicle during the hair adult homeostatic cycle, which in turn affects stem cell activation. Furthermore, we block hypomethylation of histone H3 methylation at lysines K4, K9, and K27 which we observed to occur during hair cycle. We demonstrate a critical stage-dependent role of this methylation in hair cycle and wound healing.




Our new member

We have new member, Eri, junior in Medical Sciences, joined our lab in last November. Welcome Eri! We updated “Lab Members” page.

A new paper has been published

Our lab member, Ryutaro’s paper can be read on the website.  Please find the link below for the paper. R. Ishii, H. Yanagisawa*, A. Sada*: Defining compartmentalized stem cell populations with distin

A review article has been published

A Review article by Yoshito and Hiromi has been published on the Clinical Science online website. Y. Yamashiro and H.Yanagisawa: The molecular mechanism of mechanotransduction in vascular homeostasis


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