Press Release!

Our paper on the mechanism of neointima formation has been published online.

We have shown that endothelial cells transdifferentiate into neointimal cells after blood flow cessation-induced vascular injury.

This process includes partial endothelial to mesenchymal transition triggered by hypoxia, which induces association of a11 integrin and Sharpin.

Please see this link:

https://www.tsukuba.ac.jp/journal/medicine-health/20221222141500.html